Development and Validation of UV Spectrophotometric Method for Simultaneous Determination of Rosuvastatin Calcium and Aspirin in its Pure and Pharmaceutical Dosage Forms

Development and validation of two simple, rapid, precise, accurate and sensitive UV spectrophotometric methods for the simultaneous estimation of Rosuvastatin calcium and Aspirin in bulk and in capsule dosage form. The methods are based on the measurement of absorbance of Rosuvastatin calcium and Aspirin at 241nm and 296nm respectively. The linearity of the calibration curves for Rosuvastatin calcium and Aspirin in the desired concentration range is good (r2 =0.999) by these method. The results of analysis have been validated statistically and recovery studies confirmed the accuracy of proposed methods. These methods were successfully applied to the routine determination of these drugs in bulk and in its pharmaceutical dosage form.